"I generally blog between 5:30 A.M. and 7 A.M. I will from time to time add something during the day,..." — Fred Wilson

New York's niche is content, and content is becoming more valuable. Just think about what is more valuable: MTV or the cable system that you use to get MTV? Howard Stern or the radio station you use to listen to him? Ultimately, technology becomes a commodity, and content - real, true branded content - becomes more valuable.

When I see people laughing at ideas and companies we have backed, I smile. It means we are going to make a lot of money on that investment.

We need new medical approaches to preventing and/or curing disease. We need new scientific approaches to generating, storing, and being more efficient with energy. Maybe we need more space exploration. Maybe we need more undersea exploration.

Not only do you have to put yourself in harms way in service of your country, you have to leave your families at home. It is a great sacrifice.